Nano-copper catalysed highly regioselective synthesis of 2,4-disubstituted pyrroles from terminal alkynes and isocyanides?
Chemical Communications Pub Date: 2015-07-17 DOI: 10.1039/C5CC04166J
Abstract
Nano-copper(0) stabilized on alumina prepared from Cu–Al hydrotalcite has been reported for completely regioselective synthesis of 2,4-disubstituted pyrroles from unactivated terminal aromatic/aliphatic alkynes and isocyanides. The reaction is operationally simple, involves ligand-free inexpensive nano-copper, and affords products in high yields.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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