One-pot synthesis of aryloxypropanediols from glycerol: towards valuable chemicals from renewable sources?

Green Chemistry Pub Date: 2012-12-19 DOI: 10.1039/C2GC36793A

Abstract

Glycerol offers an easy and green route for the synthesis of aryloxypropanediols of known pharmacological activity. Glycerol is selectively converted to aryloxypropanediols in a one-pot reaction, through in situ formed glycerol carbonate, under benign and solvent-free conditions. Catalyst and unreacted reagent can be recycled.

Graphical abstract: One-pot synthesis of aryloxypropanediols from glycerol: towards valuable chemicals from renewable sources
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