Recent advances and prospects in the palladium-catalyzed cyanation of aryl halides
RSC Advances Pub Date: 2020-09-11 DOI: 10.1039/D0RA05960A
Abstract
Aryl nitriles are compounds with wide significance. They have made their own space in various sectors including pharmaceuticals, industries, natural product chemistry, and so on. Furthermore, they are also key intermediates in various transformations in organic chemistry. Transition metal-catalyzed cyanation reactions have proved to be a better replacement for the existing traditional synthetic strategies for aryl nitriles. Palladium is one of the most studied transition metals other than copper and nickel owing to its wide functional group compatibility and catalytic efficacy. There have been drastic developments in the field of palladium-catalyzed cyanation since its discovery in the 1973. This review summarizes the recent developments in the palladium-catalyzed cyanation of aryl halides and covers literature from 2012–2020.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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