Phosphorylation dependent α-synuclein degradation monitored by in-cell NMR?

Chemical Communications Pub Date: 2019-08-21 DOI: 10.1039/C9CC05662A

Abstract

Here we report the dephosphorylation and proteolysis of phosphorylated α-synuclein, a Parkinson's disease-related protein, in living cells in a time resolved manner using in-cell NMR.

Graphical abstract: Phosphorylation dependent α-synuclein degradation monitored by in-cell NMR
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