Radical fluoroalkylthiolation of aldehydes with PhSO2SRf (Rf = CF3, C2F5, CF2H or CH2F): a general protocol for the preparation of fluoroalkylthioesters?
Organic Chemistry Frontiers Pub Date: 2018-05-28 DOI: 10.1039/C8QO00327K
Abstract
A general method for the preparation of fluoroalkylthioesters including trifluoromethylthio/pentafluoroethylthio/difluoromethylthio/monofluoromethylthio-esters from aldehydes and a corresponding fluoroalkylthiolating reagent was reported. The reactions were conducted under mild conditions and various common functional groups such as fluorine, chloride, bromide, iodide, and ester groups were compatible.
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Journal Name：Organic Chemistry Frontiers
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CAS no.: 89640-58-4
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