Pd-catalyzed bidentate auxiliary assisted remote C(sp3)–H functionalization
Chemical Communications Pub Date: 2021-11-10 DOI: 10.1039/D1CC05291H
Abstract
Pd-catalyzed C–H functionalisation affords effective synthetic tools to construct C–C and C–X bonds. Despite the challenges, the distal functionalization of C(sp3)–H bonds has witnessed significant developments and the use of bidentate auxiliaries has garnished this area by providing an opportunity to control reactivity as well as selectivity beyond proximal sites. This article covers the recent developments on the Pd-catalyzed bidentate auxiliary-assisted distal C(sp3)–H functionalization and is categorized based on the nature of functionalizations.
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Journal Name:Chemical Communications
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CAS no.: 89640-58-4