Mn(OAc)3-mediated arylation–lactonization of alkenoic acids: synthesis of γ,γ-disubstituted butyrolactones?
RSC Advances Pub Date: 2015-04-15 DOI: 10.1039/C5RA04429D
Abstract
A general method for the oxidative cyclization of 4-alkenoic acids with arylboronic acids has been developed. The reactions described provide a novel access to γ,γ-disubstituted butyrolactones in moderate yields, and allow the direct formation of a C–C bond and the construction of a lactone ring in one reaction.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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