Palladium-catalyzed hydroformylation of terminal arylacetylenes with glyoxylic acid?

Chemical Communications Pub Date: 2018-01-31 DOI: 10.1039/C7CC09629A

Abstract

A simple, practical and governable palladium-catalyzed hydroformylation of terminal arylacetylenes has been disclosed. The reaction proceeds under syngas-free conditions, using readily available glyoxylic acid as the formyl source, under mild conditions, giving rise to a broad range of α,β-unsaturated aldehydes.

Graphical abstract: Palladium-catalyzed hydroformylation of terminal arylacetylenes with glyoxylic acid
Recommended Literature