Palladium mediated domino reaction: synthesis of isochromenes under aqueous medium?
RSC Advances Pub Date: 2020-01-02 DOI: 10.1039/C9RA08792C
Abstract
Isochromenes have been synthesized using palladium-catalyzed C–C and C–O bond forming reactions starting from ortho-bromo tertiary benzylic alcohols and internal acetylenes. Notably, this domino process is feasible by using the green solvent, water. The protocol exhibited a broad substrate scope and afforded various isochromenes.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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