Microbial Baeyer–Villiger oxidation of terpenones by recombinant whole-cell biocatalysts—formation of enantiocomplementary regioisomeric lactones?

Organic & Biomolecular Chemistry Pub Date: 2007-04-25 DOI: 10.1039/B703175K

Abstract

Recombinant whole-cell expression systems for Baeyer–Villiger monooxygenases of various bacterial origin were utilized in the regiodivergent biooxidation of cyclic terpenones enabling access to enantio- and regioisomeric lactones on preparative scale.

Graphical abstract: Microbial Baeyer–Villiger oxidation of terpenones by recombinant whole-cell biocatalysts—formation of enantiocomplementary regioisomeric lactones
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