Modular automated solid phase synthesis of dermatan sulfate oligosaccharides?
Chemical Communications Pub Date: 2014-01-03 DOI: 10.1039/C3CC48860H
Abstract
Dermatan sulfates are glycosaminoglycan polysaccharides that serve a multitude of biological roles as part of the extracellular matrix. Orthogonally protected D-galactosamine and L-iduronic acid building blocks and a photo-cleavable linker are instrumental for the automated synthesis of dermatan sulfate oligosaccharides. Conjugation-ready oligosaccharides were obtained in good yield.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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