One-pot synthesis of benzoxazoles via the metal-free ortho-C–H functionalization of phenols with nitroalkanes?
RSC Advances Pub Date: 2015-08-18 DOI: 10.1039/C5RA15128G
Abstract
PPA-activated nitroalkanes are employed in the design of a one-pot cascade transformation involving metal-free and oxidant-free direct ortho-C–H functionalization, followed by Beckman rearrangement and intramolecular cyclocondensation to produce benzoxazoles and benzobisoxazoles directly from easily available phenols.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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