Merging cobalt and photoredox catalysis for the C8–H alkoxylation of 1-naphthylamine derivatives with alcohols?

Organic & Biomolecular Chemistry Pub Date: 2021-10-28 DOI: 10.1039/D1OB01721G

Abstract

A combined cobalt and photoredox catalysis system to realize the C8–H alkoxylation of 1-naphthylamine derivatives with alcohols was developed. Using commercially available alkyl alcohols as raw materials and Co(OAc)2 and rose bengal as catalysts, 1-naphthylamine derivatives reacted with alcohols to generate the corresponding C8–H alkoxylation products in good yields.

Graphical abstract: Merging cobalt and photoredox catalysis for the C8–H alkoxylation of 1-naphthylamine derivatives with alcohols
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