One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water

Green Chemistry Pub Date: 2012-06-19 DOI: 10.1039/C2GC35764J

Abstract

A new synthetic method for the one-pot preparation of aldoximes in water was developed; the method is based on the combination of the enzymatic oxidation of primary alcohols to aldehydes using different acetic acid bacteria and in situ condensation of the aldehydes with hydroxylamine.

Graphical abstract: One-pot chemoenzymatic synthesis of aldoximes from primary alcohols in water
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