Palladium-catalyzed oxidative cross-coupling of azole-4-carboxylates with indoles: an approach to the synthesis of pimprinine?
Organic & Biomolecular Chemistry Pub Date: 2014-11-14 DOI: 10.1039/C4OB01844C
Abstract
An efficient and straightforward method for the production of 5-(3-indolyl)azoles incorporating the privileged structures indoles and azoles via palladium-catalyzed double C–H bond cleavage under mild conditions was disclosed. As expected, this protocol provided an easy method for the synthesis of indole alkaloids pimprinine and WS-30581 A in moderate yields.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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