Palladium and copper-catalyzed ligand-free coupling of phenylhydrazines in water?

RSC Advances Pub Date: 2014-09-05 DOI: 10.1039/C4RA04621H

Abstract

An efficient protocol has been developed for the synthesis of biaryls via Pd/Cu catalyzed coupling of phenylhydrazines in water. Homo and cross couplings were successfully achieved in a ligand-free catalytic system, at room temperature with water as sole reaction medium.

Graphical abstract: Palladium and copper-catalyzed ligand-free coupling of phenylhydrazines in water
Recommended Literature