Non-toxic cyanide sources and cyanating agents

Organic & Biomolecular Chemistry Pub Date: 2018-09-25 DOI: 10.1039/C8OB02140F

Abstract

The present review gives an overview over non-toxic cyanation agents and cyanide sources used in the synthesis of structurally diverse products containing the nitrile function. Nucleophilic as well as electrophilic agents/systems that transfer the entire CN-group were taken in consideration. Reactions in which a preexisting carbon functionality is transformed into a nitrile function by addition of nitrogen are however not covered here.

Graphical abstract: Non-toxic cyanide sources and cyanating agents
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