One-pot synthesis of 2-aminoquinoline-based alkaloids from acetonitrile?
Organic & Biomolecular Chemistry Pub Date: 2012-05-08 DOI: 10.1039/C2OB25709B
Abstract
α-Diaminoboryl carbanions, readily prepared from acetonitrile, stereoselectively convert 2-nitrobenzaldehydes into nitrophenyl (Z)-acrylonitriles. Subsequent reductive cyclization leads to a series of 2-aminoquinoline derivatives. The entire procedure is practically operated in a single flask.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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