Large scale synthesis of the Cdc42 inhibitor secramine A and its inhibition of cell spreading
Organic & Biomolecular Chemistry Pub Date: 2006-10-05 DOI: 10.1039/B609143A
Abstract
We describe a large scale synthesis of secramine A. Consistent with its ability to inhibit activation of the small GTPase Cdc42, we find that secramine A inhibits cell spreading, a process previously shown to be Cdc42-dependent.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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