Organocatalytic synthesis of polysubstituted tetrahydrofurans from alkenes?
Green Chemistry Pub Date: 2016-10-26 DOI: 10.1039/C6GC02580C
Abstract
A novel, organocatalytic and environmentally friendly protocol for the synthesis of polysubstituted tetrahydrofurans from trivial starting materials has been described. By employing 2,2,2-trifluoroacetophenone-mediated oxidation, which utilizes H2O2 as a green oxidant, we introduce a sustainable procedure that embraces the principles of green chemistry for the production of substituted tetrahydrofurans in high to excellent yields and tolerates a wide range of substitution patterns.
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Journal Name：Green Chemistry
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CAS no.: 89640-58-4
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