Nickel-catalyzed C–P cross-coupling of diphenylphosphine oxide with aryl chlorides?
Organic & Biomolecular Chemistry Pub Date: 2012-10-24 DOI: 10.1039/C2OB26874D
Abstract
A novel protocol for the preparation of various diarylphosphine oxide compounds via a Ni-catalyzed cross-coupling of aryl chlorides with R2P(O)H has been developed. Notably, this process exhibits the following very attractive features: (i) the process is simpler and operates under mild reaction conditions; (ii) the process is generally cheaper in part because the more accessible aryl chloride is used to form the C–P bond; (iii) the process avoids the need for simultaneous preparation and use of Ar2P(O)M.
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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