Nickel-catalyzed acetamidation and lactamization of arylboronic acids?
Chemical Communications Pub Date: 2017-10-10 DOI: 10.1039/C7CC07055A
Abstract
A nickel-catalyzed acetamidation and lactamization of arylboronic acids via a one-pot reaction with ynamides and N-hydroxyphthalimide is described. This protocol features with mild reaction conditions and a broad substrate scope, and has been successfully applied to late-stage functionalization of pharmaceuticals. Moreover, control reactions were conducted to elucidate a plausible mechanism.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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