Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates?

Organic & Biomolecular Chemistry Pub Date: 2009-12-16 DOI: 10.1039/B916343C

Abstract

Nucleophilic heterocyclic carbenes (NHCs) have been used for the first time as catalysts in the cyclopropanation of ethyl cyanocinnamates with phenacyl bromide by Michael-initiated ring-closure (MIRC).

Graphical abstract: Nucleophilic heterocyclic carbene as a novel catalyst for cyclopropanation of cyano acrylates
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