NBS mediated nitriles synthesis through CC double bond cleavage?

Organic & Biomolecular Chemistry Pub Date: 2013-11-28 DOI: 10.1039/C3OB42118J

Abstract

An NBS mediated nitriles synthesis through C[double bond, length as m-dash]C double bond cleavage has been developed. TMSN3 was employed as the nitrogen source for this Cu(OAc)2 promoted nitrogenation reaction. This transformation has a relatively high regio-selectivity to form aromatic nitriles.

Graphical abstract: NBS mediated nitriles synthesis through C [[double bond, length as m-dash]] C double bond cleavage
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