Microwave-assisted reductive cyclization: an easy entry to the indoloquinolines and spiro[2H-indole-2,3′-oxindole]?

RSC Advances Pub Date: 2014-05-12 DOI: 10.1039/C4RA02814G

Abstract

Synthesis of two linear indoloquinolines i.e. 6H-indolo[2,3-b]quinoline & 11-hydroxy-10H-indolo[3,2-b]quinoline, and spiro[2H-indole-2,3′-oxindole] from a common intermediate, (2-nitrophenyl)methylidene-dihydro-indolone derivative is described using microwave-mediated reductive cyclization as the key step.

Graphical abstract: Microwave-assisted reductive cyclization: an easy entry to the indoloquinolines and spiro[2H-indole-2,3′-oxindole]
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