Nickel-catalyzed C–O bond reduction of aryl and benzyl 2-pyridyl ethers?
Chemical Communications Pub Date: 2018-02-01 DOI: 10.1039/C7CC09668B
Abstract
The reduction of aryl and benzyl 2-pyridyl ethers with sodium isopropoxide was carried out via nickel-catalyzed C–OPy bond cleavage, giving reductive products in reasonable to excellent yields. This method allowed the 2-pyridyloxy group to be directly removed with high efficiency, mild reaction conditions, and good compatibility of functional groups.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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