Metal-free synthesis of imidazo[1,5-a]pyridines via elemental sulfur mediated sequential dual oxidative Csp3–H amination?
Organic & Biomolecular Chemistry Pub Date: 2018-07-23 DOI: 10.1039/C8OB01391H
Abstract
A simple and efficient approach has been developed for the synthesis of imidazo[1,5-a]pyridines using the elemental sulfur mediated sequential dual oxidative Csp3–H amination of 2-pyridyl acetates and amines under metal- and peroxide-free conditions. Broad substrate scope, operational simplicity and gram-scale ability make this chemistry very practical.
![Graphical abstract: Metal-free synthesis of imidazo[1,5-a]pyridines via elemental sulfur mediated sequential dual oxidative Csp3–H amination](http://scimg.chem960.com/usr/1/C8OB01391H.jpg)
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Journal Name：Organic & Biomolecular Chemistry
research_products
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CAS no.: 89640-58-4
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