JANUS WEDGES: a new approach towards nucleobase-pair recognition
Chemical Communications Pub Date: 1900-01-01 DOI: 10.1039/CC9960002443
Abstract
The two-faced JANUS-type heterocycles 1a and 1b are designed to recognize a cytosine–uracil mismatched basepair by insertion in a wedge-like fashion between the bases to give a triad motif utilizing the maximum number of Watson–Crick interactions, as shown by 1H NMR spectroscopic studies.
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Journal Name：Chemical Communications
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