A peptide-based pH-sensitive drug delivery system for targeted ablation of cancer cells?

Chemical Communications Pub Date: 2015-08-05 DOI: 10.1039/C5CC05184C

Abstract

A peptide-guided prodrug incorporating a tumor-specific peptide, doxorubicin, and a pH-sensitive hydrazone bridge was developed for targeted ablation of cancer cells with minimal side cytotoxicity.

Graphical abstract: A peptide-based pH-sensitive drug delivery system for targeted ablation of cancer cells
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