Metal-free tandem reaction in water: An efficient and regioselective synthesis of 3-hydroxyisoindolin-1-ones?
Green Chemistry Pub Date: 2010-07-08 DOI: 10.1039/C004745G
Abstract
A mild and effective method was developed for the construction of heterocyclic building blocks 3-hydroxyisoindolin-1-ones via a metal-free tandem transformation with excellent regioselectivity. Significantly, the strategy presents an atom-economical and environmentally friendly transformation, in which two new C–N bonds and one C–O bond are formed in
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Journal Name:Green Chemistry
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CAS no.: 89640-58-4