Metal-free in situ sp3, sp2, and sp C–H functionalization and oxidative cross coupling with benzamidines hydrochloride: a promising approach for the synthesis of α-ketoimides?
RSC Advances Pub Date: 2014-11-11 DOI: 10.1039/C4RA07556K
Abstract
A new metal-free tandem protocol for the synthesis of α-ketoimides via sp3, sp2, and sp C–H functionalization followed by oxidative cross coupling with benzamidines hydrochloride using catalytic iodine with TBHP in DMSO has been developed. A wide range of functional group tolerance, an inexpensive catalyst, operational simplicity and good to excellent yields of the products are the striking features of this method.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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