Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group?

RSC Advances Pub Date: 2018-12-21 DOI: 10.1039/C8RA08584F

Abstract

The antibiotic penicillin G cannot be completely incorporated into hydrophobic lipid-membranes owing to its hydrophilicity. Through modification with a hydrophobic and photolabile protecting group, penicillin G was effectively incorporated into liposomes and released by photoirradiation at 365?nm.

Graphical abstract: Light-triggered hydrophilic drug release from liposomes through removal of a photolabile protecting group
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