Leveraging synthetic chlorins for bio-imaging applications?

Chemical Communications Pub Date: 2020-09-10 DOI: 10.1039/D0CC05494A

Abstract

Synthetic chlorins are not only fluorescent, the modulation of the tetrapyrrole system can also chelate metal ions. Conjugation of linkers at their pyrrolidines allows for conjugation to bio-molecules to create target specificity. By altering these chemo-photophysical properties, this work facilitates the use of chlorins in fluorescent imaging and positron emission tomography (PET).

Graphical abstract: Leveraging synthetic chlorins for bio-imaging applications
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