Library of second-generation cycloruthenated compounds and evaluation of their biological properties as potential anticancer drugs: Passing the nanomolar barrier?
Dalton Transactions Pub Date: 2011-08-12 DOI: 10.1039/C1DT10322A
Abstract
A library of 32 organoruthenium compounds has been synthesised. Known and novel C–N cyclometalated compounds as well as N–C–N and N–N–C pincer derivatives of this metal have been used in this purpose. Most of the compounds have been tested for their in vitro antitumoral behaviours, good to excellent activities have thus been found. Several of the newly synthesized compounds pass the symbolic barrier of the nanomolar range for their
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Journal Name:Dalton Transactions
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CAS no.: 89640-58-4