Imidazole modified Pt(iv) prodrug-loaded multi-stage pH responsive nanoparticles to overcome cisplatin resistance?
Chemical Communications Pub Date: 2020-08-14 DOI: 10.1039/D0CC01846E
Abstract
An imidazole modified Pt(IV) prodrug with a long lipid tail can assemble into multi-stage pH responsive nanoparticles via electrostatic complexation with a negatively charged hydrophilic polymer. This strategy could overcome cisplatin resistance significantly.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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