Iridium catalysed chemoselective alkylation of 2′-aminoacetophenone with primary benzyl type alcohols under microwave conditions?

Chemical Communications Pub Date: 2012-03-20 DOI: 10.1039/C2CC31055D

Abstract

2′-Aminoacetophenone was chemoselectively alkylated with a range of substituted benzyl, heteroaryl alcohols to afford either the corresponding C- or N- alkylated products in good yield.

Graphical abstract: Iridium catalysed chemoselective alkylation of 2′-aminoacetophenone with primary benzyl type alcohols under microwave conditions
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