Intracellular click reaction with a fluorescent chemical Ca2+ indicator to prolong its cytosolic retention?
Chemical Communications Pub Date: 2013-05-16 DOI: 10.1039/C3CC42489H
Abstract
The powerful strategy of “intracellular click reaction” was used to retain a chemical Ca2+ indicator in the cytosol. Specifically, a novel clickable Ca2+ indicator “N3-fura-2 AM” was coupled with dibenzylcyclooctyl-modified biomacromolecules via copper-free click reaction in living cells and Ca2+ oscillation was observed for an extended period of time.
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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