A novel cationic triazatetrabenzcorrole: selective detection of mercury(ii) by nucleic acid-induced aggregation?

Analyst Pub Date: 2010-12-15 DOI: 10.1039/C0AN00927J

Abstract

In the present work, a novel water-soluble cationic triazatetrabenzcorrole compound was synthesised. Its aggregation and fluorescence quenching properties are demonstrated by serval methods, such as UV-vis and fluorescence spectroscopic studies and naked-eye visualization. Unlike the traditional Hg2+ sensor based on thymine–Hg2+–thymine, we use a novel approach, exploiting the high affinity of Hg2+ for sulfur in phosphorothioate DNA. Based on the S–Hg2+–S pairs, we designed the phosphorothioate DNA T4G4-S3 as an Hg2+ sensor, which can detect Hg2+ sensitively and selectively in aqueous solution. And this sensing system is fairly fast and convenient.

Graphical abstract: A novel cationic triazatetrabenzcorrole: selective detection of mercury(ii) by nucleic acid-induced aggregation
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