Highly practical iron-catalyzed C–O cleavage reactions?

Catalysis Science & Technology Pub Date: 2013-06-14 DOI: 10.1039/C3CY00266G

Abstract

Facile iron-catalyzed cleavage of various allyl, cinnamyl and benzyl C–O linkages has been effected in the presence of ethylmagnesium chloride. The protocol is operationally simple (xylene–THF, r.t., 1 h), requires low catalyst loading (1 mol% FeCl2) and tolerates halides, esters, amines, ethers and olefins. The allyl moiety is converted to volatile hydrocarbons which renders laborious product separation unnecessary.

Graphical abstract: Highly practical iron-catalyzed C–O cleavage reactions
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