Highly enantioselective synthesis of angelmarin?

Organic & Biomolecular Chemistry Pub Date: 2009-08-04 DOI: 10.1039/B913400J

Abstract

Angelmarin (1), a novel anti-cancer agent, was efficiently synthesized through a highly enantioselective epoxidation and a copper cyanide-mediated esterification of the hindered alcohol as the key steps in 53% overall yield.

Graphical abstract: Highly enantioselective synthesis of angelmarin
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