Highly enantioselective iron(ii)-catalyzed opening reaction of aromatic meso-epoxides with indoles?
Organic & Biomolecular Chemistry Pub Date: 2013-09-26 DOI: 10.1039/C3OB41782D
Abstract
A highly enantioselective method for the catalytic cis-stilbene oxide opening reaction with indole derivatives was developed. The scope of the reaction was studied with a selection of aromatic meso-epoxides and various indoles, and the desired 2-(indol-3-yl)ethanol derivatives were obtained in good to excellent yields with excellent enantioselectivities (from 96 to >99% ee).
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Journal Name：Organic & Biomolecular Chemistry
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CAS no.: 89640-58-4
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