A non-metal catalysed oxidation of primary azides to nitriles at ambient temperature?

Organic & Biomolecular Chemistry Pub Date: 2012-01-10 DOI: 10.1039/C2OB06949K

Abstract

A novel non-metal catalyzed oxidation of organic azides to nitriles under solvent-free conditions is presented employing catalytic amounts of KI, and DABCO in aq. TBHP at room temperature. This non-metal catalyzed oxidation of azides provides good selectivity as double and triple bonds were not oxidized under the present reaction conditions.

Graphical abstract: A non-metal catalysed oxidation of primary azides to nitriles at ambient temperature
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