Identification and characterization of an anthrol reductase from Talaromyces islandicus (Penicillium islandicum) WF-38-12?
Green Chemistry Pub Date: 2019-11-06 DOI: 10.1039/C9GC03072G
Abstract
An NADPH-dependent oxidoreductase from Talaromyces islandicus WF-38-12 has been identified through genome analysis. It has been shown to catalyze a regio- and stereoselective reduction of anthrols (formed in situ by the reduction of anthraquinones in the presence of Na2S2O4) to (R)-dihydroanthracenones, with high enantiomeric excess (>99%). The implications of results on the biosynthesis of deoxygenated (bis)anthraquinones and modified (bis)anthraquinones are discussed.
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Journal Name：Green Chemistry
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CAS no.: 89640-58-4
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