A new l-lysine derived highly molecular-shape selective organic phase with ordered functional groups for reversed-phase liquid chromatography?

Analytical Methods Pub Date: 2014-03-10 DOI: 10.1039/C4AY00368C

Abstract

An L-lysine-based urea containing low-molecular-weight organogelator was synthesized and grafted onto silica particles, so that the functional groups were expected to be oriented through H-bonding. The gelator-grafted particles were applied for the separation of bioactive and shape-constrained isomers for the first time and they showed very high molecular shape-selectivity.

Graphical abstract: A new l-lysine derived highly molecular-shape selective organic phase with ordered functional groups for reversed-phase liquid chromatography
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