Hydrogen peroxide-responsive micelles self-assembled from a peroxalate ester-containing triblock copolymer?
Biomaterials Science Pub Date: 2015-12-14 DOI: 10.1039/C5BM00391A
Abstract
A novel ABA triblock copolymer by using peroxalate esters as linkages was synthesized. In water, this amphiphilic copolymer self-assembled into micelles which were used as drug delivery carriers. When stimulated with hydrogen peroxide, the micelles disassembled to release drugs since the responsive peroxalate ester linkages would be cleaved after the reaction with hydrogen peroxide.
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Journal Name:Biomaterials Science
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CAS no.: 89640-58-4