Facile synthesis of magnetic homochiral metal–organic frameworks for “enantioselective fishing”?

Chemical Communications Pub Date: 2015-01-22 DOI: 10.1039/C4CC09988E

Abstract

Magnetic functionalized homochiral metal–organic frameworks (MOFs) were prepared and applied to efficient enantioselective fishing of chiral drug intermediates. Under optimized conditions, the enantiomeric excess (ee) value as high as 85.2% was achieved for methyl phenyl sulfoxide (MPS) within 3 min.

Graphical abstract: Facile synthesis of magnetic homochiral metal–organic frameworks for “enantioselective fishing”
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