A new [2 + 2] photodimerization of 5-chloro- and 5-methyl-2-pyridone in their inclusion complexes with 1,1′-biphenyl-2,2′-dicarboxylic acid as a model for DNA damage by photodimerization of its thymine component
Chemical Communications Pub Date: 2004-12-13 DOI: 10.1039/B414134B
Abstract
As a model for DNA damage by photodimerization of its thymine component, a new [2 + 2] photodimerization of 5-chloro and 5-methyl-2-pyridone to the corresponding cis-anti-dimers as their inclusion complexes with 1,1′-biphenyl-2,2′-dicarboxylic acid was found, and the mechanism of this stereoselective solid state reaction was studied by X-ray analysis.
![Graphical abstract: A new [2 + 2] photodimerization of 5-chloro- and 5-methyl-2-pyridone in their inclusion complexes with 1,1′-biphenyl-2,2′-dicarboxylic acid as a model for DNA damage by photodimerization of its thymine component](http://scimg.chem960.com/usr/1/B414134B.jpg)
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Journal Name：Chemical Communications
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CAS no.: 89640-58-4
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