(?)-Bacillamide C: the convergent approach ??

Organic & Biomolecular Chemistry Pub Date: 2009-11-26 DOI: 10.1039/B918214D

Abstract

The newly discovered natural product bacillamide C and several derivatives were convergently synthesized for the first time and in only three steps. The key transformation constitutes a thiazole Ugi multicomponent reaction. These compounds will serve to elucidate chemical biology and SAR of this potent anti-algae natural product and shows the synthetic pathway to related natural products.

Graphical abstract: (?)-Bacillamide C: the convergent approach
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