Enantio-differentiation of molecules with diverse functionalities using a single probe?

Chemical Communications Pub Date: 2015-07-16 DOI: 10.1039/C5CC05290D

Abstract

This study reports (1S,2S)-N,N′-dihydroxy-N,N′-bis(diphenylacetyl)-1,2-cyclohexanediamine, a C2 symmetric chiral hydroxamic acid ((S)-CBHA-DPA), as a unique probe for discrimination of molecules with diverse functionalities. The proposed CSA is also utilized for the accurate measurement of enantiomeric excess.

Graphical abstract: Enantio-differentiation of molecules with diverse functionalities using a single probe
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