A naphthalimide-based turn-on fluorescence probe for peroxynitrite detection and imaging in living cells?
RSC Advances Pub Date: 2020-10-16 DOI: 10.1039/D0RA06564A
Abstract
Peroxynitrite (ONOO?) is a potent biological oxidant that plays a significant role in diverse physiological and pathological processes. A novel fluorescent probe HCA-OH was developed for specific and sensitive detection of peroxynitrite, and displayed a significant fluorescence turn-on signal. With low cytotoxicity and good photostability, the probe HCA-OH could be applied in imaging ONOO? distribution in HepG2 cells and live C. elegans in real time. Therefore, the probe can be a promising tool for imaging in vivo.
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Journal Name：RSC Advances
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CAS no.: 89640-58-4
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